C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 19/00 (2006.01) A61K 38/17 (2006.01) A61K 38/18 (2006.01) C07K 14/46 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01)
Patent
CA 2269221
A hedgehog conjugate which is characterized in that it contains: a) a polypeptide composed of 10 to 30 hydrophobic amino acids and/or amino acids which form transmembrane helices and are positively charged, b) 1 to 4 aliphatic, saturated or unsaturated hydrocarbon residues with a chain length of 10 to 24 C atoms and with a hydrophobic action or c) a hydrophobic thio compound covalently bound to a hedgehog protein and which has a several-fold increased activity and is suitable as a pharmaceutical agent.
Esswein Angelika
Lang Kurt
Rueger Petra
Seytter Tilman
Curis Inc.
Gowling Lafleur Henderson Llp
Roche Diagnostics Gmbh
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