Active immunization against angiogenesis-associated antigens

Details Active immunization against angiogenesis-associated antigens Active immunization against angiogenesis-associated antigens

C - Chemistry, Metallurgy

07

H

C07H 21/02 (2006.01) A01N 63/00 (2006.01) A61K 39/00 (2006.01) A61K 39/395 (2006.01) C12N 9/96 (2006.01) C12N 15/00 (2006.01)

Patent

CA 2310252

Modified angiogenic self antigens and anti-idiotypic antibodies that mimic an antigenic determinant of a receptor to an angiogenic molecule are provided. In vitro and in vivo methods of using these antigens and antibodies are also provided.

Cette invention se rapporte à des antigènes du soi angiogéniques modifiés et à des anticorps anti-idiotypiques, qui imitent un déterminant antigénique d'un récepteur contre une molécule angiogénique. Des procédés in vitro et in vivo d'utilisation de ces antigènes et de ces anticorps sont également présentés.

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