Active specific immunotherapy of adenocarcinomas producing...

Details Active specific immunotherapy of adenocarcinomas producing... Active specific immunotherapy of adenocarcinomas producing...

A - Human Necessities

61

K

167/103, 167/215

A61K 39/00 (2006.01) A61K 31/535 (2006.01) A61K 31/675 (2006.01) A61K 31/70 (2006.01) A61K 35/14 (2006.01) A61K 35/26 (2006.01) A61K 45/00 (2006.01) C12N 5/08 (2006.01)

Patent

CA 2013966

A synergistic composition is provided herein for inhibiting the growth of an adenocarcinoma tumour. The tumour is associated with a mucin having immunosuppressive activity. The composition comprises: an immune-response-potentiating amount of cyclophosphamide, and an immuno-genically-effective amount of a carbohydrate epitope-bearing antigen. Such antigen is immunologically cross-reactive with a mucin having immunosuppressive activity associated with the tumour.

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