A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4468 (2006.01) A61K 31/135 (2006.01) A61K 31/452 (2006.01) A61P 25/04 (2006.01)
Patent
CA 2406976
The invention relates to an active substance combination that contains as the active substance component a) at least one opioid compound that has a fentanyl- type structure and/or the enantiomers and/or the diastereomers thereof and/or at least one corresponding pharmaceutically acceptable salt, and as the active substance component b) ketamine and/or at least one of its physiologically acceptable salts. The weight ratio of active substance component a) to active substance component b) ranges from 1:20 to 1:1500. The invention also relates to medicament formulations and medicaments that contain the inventive active substance combination and to the use of said active substance combination for producing medicaments.
La présente invention concerne une combinaison de principes actifs contenant, comme composant a), au moins un composé opioïde présentant une structure du type fentanyle et/ou ses énantiomères et/ou ses diastéréomères et/ou au moins un sel pharmaceutiquement acceptable correspondant, et, comme composant b), de la cétamine et/ou au moins un de ses sels physiologiquement compatibles, le rapport pondéral du composant a) au composant b) étant compris dans la plage 1:20-1:1500. L'invention concerne également des formulations de médicaments et des médicaments contenant cette combinaison de principes actifs, ainsi que l'utilisation de celle-ci pour la production de médicaments.
Chizh Boris
Christoph Thomas
Englberger Werner
Borden Ladner Gervais Llp
Gruenenthal Gmbh
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