Activin receptor-like kinases, proteins having serine...

Details Activin receptor-like kinases, proteins having serine... Activin receptor-like kinases, proteins having serine...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/18 (2006.01) A61K 38/45 (2006.01) C07K 14/71 (2006.01) C07K 16/28 (2006.01) C07K 16/40 (2006.01) C12N 9/12 (2006.01) C12N 15/54 (2006.01) G01N 33/566 (2006.01) G01N 33/573 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2149441

A new receptor family has been identified, of activin-like kinases. Novel proteins have activin/TGF-.beta.-type I receptor func- tionality, and have consequential diagnostic/therapeutic utility. They may have a serine/threonine kinase domain, a DFKSRN or DLKSKN sequence in subdomain VIB and/or a GTKRYM sequence in subdomain VIII.

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