C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/59 (2006.01) A61K 35/55 (2006.01) A61K 38/16 (2006.01) A61K 38/24 (2006.01) A61P 15/08 (2006.01) C12N 15/16 (2006.01)
Patent
CA 2707352
The present invention provides methods of producing biologically active recombinant eFSH analogs and methods of increasing reproduction in mammals, particularly equine, using recombinant eFSH analogs. Also provided are methods of producing biologically active single chain recombinant eFSH. The recombinant eFSH analogs of the present invention increase superovulation, follicular development, embryo development, and reproductive efficiency in horses, cattle and other ungulates.
La présente invention propose des procédés de production d'analogues d'eFSH recombinants biologiquement actifs et des procédés d'augmentation de reproduction chez les mammifères, en particulier chez des équidés, en utilisant des analogues d'eFSH recombinants. L'invention propose également des procédés de production d'eFSH recombinants à chaîne unique biologiquement actifs. Les analogues d'eFSH recombinants de la présente invention augmentent la super-ovulation, le développement folliculaire, le développement embryonnaire et l'efficacité de reproduction chez les chevaux, le bétail et autres ongulés.
Boime Irving
Colgin Mark
Niswender Kory
Roser Janet
Aspenbio Pharma Inc.
Boime Irving
Colgin Mark
Mckay-Carey & Company
Niswender Kory
LandOfFree
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