Actriib fusion polypeptides and uses therefor

Details Actriib fusion polypeptides and uses therefor Actriib fusion polypeptides and uses therefor

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A61K 38/17 (2006.01) A61K 47/48 (2006.01) C07K 14/705 (2006.01) C07K 14/71 (2006.01) C07K 16/18 (2006.01) C07K 19/00 (2006.01) C12N 15/12 (2006.01) C12N 15/13 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2501180

Methods and compositions for inhibiting growth and differentiation factor-8 (GDF-8) activity in vitro and in vivo are provided.The methods and composition can be used for diagnosing, preventing, or treating degenerative disorders of muscle, bone, or glucose homeostasis.

L'invention concerne des procédés et des compositions permettant d'inhiber l'activité du facteur 8 de croissance et de différenciation (GDF-8) in vitro et in vivo. Les procédés et compositions de l'invention peuvent servir à diagnostiquer, à prévenir, ou à traiter des troubles dégénératifs d'ordre musculaire, osseux ou associés à l'homéostasie du glucose.

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