Acyclovir derivatives for topical use

A - Human Necessities – 61 – K

Patent

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A61K 31/70 (2006.01) A61K 31/52 (2006.01) A61K 31/675 (2006.01)

Patent

CA 2162574

Compositions for topical use in herpes virus infections comprising anti-herpes nucleoside analogue phosphate esters, such as acyclovir monophophate and acyclovir diphosphate, which show increased activity against native strains of herpes virus as well as against resistant strains, particularly thymidine kinase negative strains of virus. Also disclosed are methods for using the topical comopsitions in treatment of herpes disease.

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