C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 211/26 (2006.01) A61K 31/4545 (2006.01) A61K 31/495 (2006.01) A61P 3/00 (2006.01) C07D 401/14 (2006.01) C07D 417/14 (2006.01)
Patent
CA 2672059
Bipiperidyl compounds of the formula: (I) are disclosed as useful for treating or preventing type 2 diabetes and similar conditions. Pharmaceutically acceptable salts and solvates are included as well. The compounds are useful as agonists of the g-protein coupled receptor GPR-119.
La présente invention concerne des composés bipipéridinyle de formule : (I) utiles dans le traitement ou la prévention du diabète de type 2 et d'affections similaires. Les sels et les solvates acceptables d'un point de vue pharmaceutique sont aussi bien compris. Les composés sont utiles en tant qu'agonistes du récepteur couplé à des protéines G, GPR-119.
Adams Alan D.
Freeman Stanley
Huang Yong
Mosley Ralph T.
Santini Conrad
Gowling Lafleur Henderson Llp
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
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