Acyl derivatives of rapamycin

C - Chemistry – Metallurgy – 07 – D

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260/237.2

C07D 498/18 (2006.01)

Patent

CA 1159054

-10- AHP-7681 ABSTRACT OF THE DISCLOSURE Disclosed are monoacyl and diacyl derivatives of rapamycin, processes for their preparation, methods of using the derivatives and pharma- ceutical compositions of the derivatives. The derivatives are useful, inter alia, as antifungal antibiotics.

382848

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