C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/207, 260/260
C07D 213/70 (2006.01) C07C 59/68 (2006.01) C07D 233/84 (2006.01) C07D 239/38 (2006.01) C07D 277/36 (2006.01) C07D 285/125 (2006.01) C07D 303/48 (2006.01) C07D 333/62 (2006.01)
Patent
CA 1249823
ABSTRACT Amide Derivatives Acylanilides of the formula Image wherein R1 and R2, the same or different, each is cyano, carbamoyl, nitro, halogeno, perfluoroalkyl or other defined substituents; R3 is hydrogen or halogen; R4 is hydrogen or alkyl, or is joined to R5; R5 is hydrogen, hydroxy, alkoxy or acyloxy or is joined to R4; R6 is alkyl or halogenoalkyl, or has the formula -A3-R8 or -A4-X2-A5-R9; A1 and A4, the same or different, each is alkylene; A2, A3 and A5, the same or different, each is a direct link or alkylene; X1 and X2, the same or different, each is oxygen, sulphur, sulphinyl, sulphonyl, imino or alkylimino; R7 and R9, the same or different, each is alkyl, alkenyl, hydroxyalkyl, cycloalkyl, phenyl optionally substituted, naphthyl or heterocyclic optionally substituted; and R8 is phenyl, naphthyl or heterocyclic as defined above for R7 or R9; proceses for their manufcture and pharmaceutical compositions containing them. The acylanilides possess antiandrogenic activity.
432811
Astrazeneca Uk Limited
Smart & Biggar
LandOfFree
Acylanilides having antiandrogenic properties does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Acylanilides having antiandrogenic properties, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Acylanilides having antiandrogenic properties will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1275268