Acylated aminoalkanimidazoles and -triazoles

Details Acylated aminoalkanimidazoles and -triazoles Acylated aminoalkanimidazoles and -triazoles

C - Chemistry, Metallurgy

07

D

C07D 233/61 (2006.01) A61K 31/4196 (2006.01) A61K 31/44 (2006.01) C07D 401/06 (2006.01) C07D 409/06 (2006.01) C07D 521/00 (2006.01) A61K 31/41 (2006.01) C07D 249/08 (2006.01)

Patent

CA 2149459

The invention concerns azole compounds of formula Image wherein the substituents have various significances, in free form or salt form. They can be prepared e.g. by acylation, or by aziridine or oxazole ring opening. The compounds can be used as pharmaceuticals, especially as selective inhibitors of the 25-hydroxyvitamin D3 - hydroxylases in the treatment of disorders of proliferation and differentiation in vitamin D - responsive tissues.

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