Acylated enol derivatives as prodrugs of elastase inhibitors

Details Acylated enol derivatives as prodrugs of elastase inhibitors Acylated enol derivatives as prodrugs of elastase inhibitors

C - Chemistry, Metallurgy

07

K

C07K 5/04 (2006.01) A61K 38/05 (2006.01) A61K 38/06 (2006.01) A61K 38/07 (2006.01) C07C 271/22 (2006.01) C07K 5/023 (2006.01) C07K 5/06 (2006.01) C07K 5/08 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2191844

This invention relates to acylated enol derivatives of known elastase inhibitors. These compounds are useful in the treatment of various inflammatory diseases, including cystic fibrosis and emphysema or as prodrugs of compounds which are useful in the treatment of said diseases.

La présente invention concerne des dérivés énol acylé d'inhibiteurs connus de l'élastase. Ces composés sont utiles pour le traitement de diverses affections inflammatoires, et notamment de la fibrose kystique et de l'emphysème ou comme promédicaments pour des composés utiles dans le traitement de ces affections.

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