C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 241/04 (2006.01) A61K 31/395 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) A61K 31/496 (2006.01) A61P 25/28 (2006.01) C07D 211/16 (2006.01) C07D 295/185 (2006.01) C07B 61/00 (2006.01)
Patent
CA 2450074
The present invention relates to acyclic piperazine and piperidine derivatives, which are especially useful for treating or preventing neuronal damage, particularly damage associated with neurological diseases. These compounds are also useful for stimulating nerve growth. The invention also provides compositions comprising the compounds of the present invention and methods of utilizing those compositions for treating or preventing neuronal damage or for stimulating nerve growth.
L'invention concerne des dérivés de pipérazine et de pipéridine acycliques, particulièrement utiles dans le traitement ou la prévention de troubles neuronaux, notamment les troubles associés à des maladies neurologiques. Ces composés sont également utiles pour stimuler la croissance neuronale. L'invention concerne également des compositions comprenant lesdits composés, et des procédés d'utilisation de ces compositions dans le traitement ou la prévention de troubles neuronaux ou pour stimuler la croissance neuronale.
Botfield Martyn
Lauffer David
Ottow Eckard
Tomlinson Ronald
Smart & Biggar
Vertex Pharmaceuticals Incorporated
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