C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 271/22 (2006.01) A61K 31/27 (2006.01) A61P 7/04 (2006.01) A61P 17/00 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2612292
Acyloxyalkyl carbamate prodrugs of trans-4-(aminomethyl)- cyclohexanecarboxylic acid, pharmaceutical compositions thereof, methods of making prodrugs of trans-4-(aminomethyl)-cyclohexane-carboxylic acid, and methods of using prodrugs of trans-4-(aminomethyl)-cyclohexanecarboxylic acid and pharmaceutical compositions thereof to treat or prevent various diseases or disorders are disclosed. Acyloxyalkyl carbamate prodrugs of trans-4- (aminomethyl)- cyclohexanecarboxylic acid and pharmaceutical compositions thereof suitable for oral and topical administration and for administration using sustained release dosage forms are also disclosed.
L'invention concerne des prodrogues de carbamate d'acyloxyalkyle d'acide trø<=s-4-(aminométhyl)- cyclohexanecarboxylique, leurs compositions pharmaceutiques, les procédés de production de prodrogues d'acide tra<=s-4-(aminométhyl)-cyclohexane-carboxylique, et les procédés d'utilisation des prodrogues d'acide trans-4-(aminométhyl)-cyclohexanecarboxylique et leurs compositions pharmaceutiques pour traiter ou prévenir divers maladies ou troubles. L'invention concerne également des prodrogues de carbamate d'acyloxyalkyle d'acide tra<=s-4-(aminométhyl)- cyclohexanecarboxylique et leurs compositions pharmaceutiques adaptées à une administration orale et topicale et à une administration de formes dosifiées à libération prolongée.
Gallop Mark A.
Jandeleit Bernd
Li Yunxiao
Zerangue Noa
Gowling Lafleur Henderson Llp
Xenoport Inc.
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