C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/04 (2006.01) A61K 31/404 (2006.01) A61P 5/00 (2006.01)
Patent
CA 2492224
The invention concerns acyloxypyrrolidine derivatives of general formula (I), wherein: R¿1? represents a hydrogen atom, a C¿1?-C¿6 ?alkyl, a C¿3?-C¿6? cycloalkyl, a -CH¿2?CH¿2?COOH group or a -NR¿2?R¿3? group; R¿2? and R¿3? each independently represent a hydrogen atom or a C¿1?-C¿6? alkyl. The invention also concerns a method for preparing said derivatives and their therapeutic use.
L'invention concerne des dérivés d'acyloxypyrrolidine, de formule générale (I): dans laquelle: R¿1? représente un atome d'hydrogène, un (C¿1?-C¿6?)alkyle, un (C¿3?-C¿6?)cycloalkyle, un groupe -CH¿2?CH¿2?COOH ou un groupe -NR¿2?R¿3?; -R¿2? et R¿3? représentent chacun indépendamment un atome d'hydrogène ou un (C¿1?-C¿6?)alkyle. Procédé de préparation et application en thérapeutique.
Aulombard Alain
Garcia Georges
Pradines Antoine
Serradeil-Le Gal Claudine
Wagnon Jean
Kirby Eades Gale Baker
Sanofi-Aventis
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