Acylpeptides

Details Acylpeptides Acylpeptides

C - Chemistry, Metallurgy

07

K

530/7.06, 530/7.

C07K 14/655 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1161033

Case 4-12637/+ Novel acylpeptides Abstract Acylpeptides derived from somtostatin or from a derivative thereof having analogous action, in which the amino acids sequence is modified by omitting individual amino acids and/or by exchanging them for other amino acids, and in which the -amino group of the lysine residue in the 9-position, and optionally also the .epsilon.-amino group of the lysine residue in the 4-position and/or the N-terminal .alpha.-amino group carries the acyl radical of an optionally substituted alkanecarboxylic acid, and salts and complexes thereof can be used as antidiabetics and/or for combating gastrointestinal bleeding. They are manufactured by conventional methods of peptide chemistry.

366718

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