Adam-9 modulators

Details Adam-9 modulators Adam-9 modulators

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61P 35/00 (2006.01) C07K 16/28 (2006.01) C07K 16/30 (2006.01) C07K 16/40 (2006.01) C12N 5/16 (2006.01) C12N 15/63 (2006.01) C12P 21/08 (2006.01) G01N 33/574 (2006.01) C07K 14/705 (2006.01) C12N 9/64 (2006.01)

Patent

CA 2596273

The invention provides the identification and characterization of a disease and cancer-associated antigen, KID24. The invention also provides modulators of KID24, including a family of monoclonal antibodies that bind to antigen KID24, and methods of diagnosing and treating various human cancers and diseases associated with KID24.

L'invention vise à identifier et à caractériser une maladie et un antigène KID24 associé au cancer. Cette invention concerne les modulateurs de KID24, y compris une famille d'anticorps monoclonaux se liant à l'antigène KID24, et des méthodes de diagnostic et de traitement de cancers humains variés et de maladies associées au KID24.

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