Adam polynucleotides and polypeptides

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 9/64 (2006.01) A61K 38/43 (2006.01) C12N 15/57 (2006.01) C12N 15/74 (2006.01) C12N 15/79 (2006.01) C12Q 1/37 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2373638

The present invention relates to novel human ADAM polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human ADAM polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human ADAM polypeptides.

Cette invention a trait à de nouveaux polypeptides ADAM humains ainsi qu'à des acides nucléiques isolés renfermant les régions codantes des gènes codant ces polypeptides. L'invention porte également sur des vecteurs, des cellules hôtes, des anticorps et des techniques de recombinaison permettant de produire ces polypeptides ADAM humains. Elle concerne, de surcroît, des méthodes diagnostiques et thérapeutiques des plus utiles en matière de diagnostic et de traitement de troubles liés à ces nouveaux polypeptides ADAM humains.

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