Adamantane derivatives

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 235/46 (2006.01) A61K 31/166 (2006.01) A61K 31/167 (2006.01) A61P 37/00 (2006.01) C07C 233/01 (2006.01) C07C 233/65 (2006.01) C07C 233/88 (2006.01) C07C 235/42 (2006.01) C07C 237/30 (2006.01) C07C 323/25 (2006.01) C07D 233/54 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2393352

The invention provides adamantane derivatives of formula (I), a process for their preparation, pharmaceutical compositions containing them, a process for preparing the pharmaceutical compositions, and their use in therapy. In formula (I) D represents CH2 or CH2CH2, E represents C(O)NH or NHC(O) and R3 represents a group of formula (I).

La présente invention concerne des dérivés d'adamantane de formule (I), un procédé de préparation de ces dérivés, des compositions pharmaceutiques contenant ces derniers, un procédé de préparation desdites compositions pharmaceutiques et l'utilisation de ces dernières en thérapie. Dans la formule (I), D représente CH¿2? ou CH¿2?CH¿2?, E représente C(O)NH ou NHC(O) et R?3¿ représente un groupe de formule (I).

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