C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/06 (2006.01) A61K 31/44 (2006.01) A61K 31/445 (2006.01) C07D 207/02 (2006.01) C07D 213/24 (2006.01) C07D 213/72 (2006.01)
Patent
CA 2568241
The present invention relates to compounds which are inhibitors of the 11-beta- hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome, and other diseases and conditions that are mediated by excessive glucocorticoid action.
La présente invention a trait à des composés qui sont inhibiteurs de l'enzyme de type 1 de la 11-bêta-hydroxystéroïde déshydrogénase. La présente invention a également trait à l'utilisation d'inhibiteurs de l'enzyme de type 1 de la 11-bêta-hydroxystéroïde pour le traitement du diabète non insulino-dépendant de type 2, de la résistance à l'insuline, de l'obésité, de troubles lipidiques, du syndrome métabolique, et d'autres maladies et conditions causés par l'intermédiaire d'action glucocorticoïde excessive.
Link James T.
Patel Jyoti R.
Pliushchev Marina A.
Rohde Jeffrey J.
Shuai Qi
Abbott Laboratories
Torys Llp
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