Adamantyl benzamide compounds

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 213/60 (2006.01) A61K 31/44 (2006.01) A61K 31/50 (2006.01) A61K 31/505 (2006.01) A61P 3/00 (2006.01) A61P 9/00 (2006.01) A61P 25/00 (2006.01) C07C 213/10 (2006.01) C07D 237/14 (2006.01) C07D 239/42 (2006.01)

Patent

CA 2744383

Embodiments of the present invention provide adamantyl benzamide derivtives and pharmaceutical compositions comprising adamantyl benzamide derivatives. Methods of use of such compounds and compositions to modulate the activity of 11.beta.-hydroxysteroid dehydrogenase type 1(11.beta.HSD1) in a subject are also provided.

Les modes d'application de la présente invention concernent des dérivés de benzamide de type adamantyle et des compositions pharmaceutiques comportant des dérivés de benzamide de type adamantyle. La présente invention concerne également des méthodes d'emploi de tels composés et compositions dans la modulation de lactivité de la 11ß-hydroxystéroïde déshydrogénase de type 1 (11ßHSD1).

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