G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/574 (2006.01) A61K 45/00 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) C07K 16/18 (2006.01)
Patent
CA 2598004
ADAMTS-7 expression and activity are up regulated in patients that have cancers of epithelial origin. Accordingly, the present invention is directed to methods diagnosis of cancers of epithelial origin (e.g. breast cancer, prostate cancer, bladder cancer, brain cancer and hepatic cancer). In particular, the presence of ADAMTS-7 in a biological sample is indicative of cancer of epithelial origin. Thus, measuring the level of ADAMTS-7 in biological samples (e.g. urine or blood) provides a quick, easy, and safe screen that can be used to diagnose cancer in a patient.
L'expression et l'activité de la protéine ADAMTS-7 sont régulées à la hausse chez des patients souffrant de cancers d'origine épithéliale. L'invention concerne des méthodes diagnostiques de cancers d'origine épithéliale (par exemple, cancer du sein, cancer de la prostate, cancer de la vessie, cancer du cerveau et cancer du foie). En particulier, la présence de la protéine ADAMTS-7 dans un échantillon biologique indique un cancer d'origine épithéliale. Ainsi, la mesure du niveau de la protéine ADAMTS-7 dans des échantillons biologiques (par exemple, de l'urine ou du sang) permet d'obtenir un dépistage rapide, facile et sûr servant à diagnostiquer un cancer chez un patient.
Moses Marsha A.
Roy Roopali
Children's Medical Center Corporation
Smart & Biggar
LandOfFree
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