C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/37 (2006.01) A61K 38/43 (2006.01) A61P 7/02 (2006.01) A61P 9/10 (2006.01)
Patent
CA 2606351
This invention relates to a pharmaceutical composition having thrombolytic activity comprising ADAMTS13, and to methods for treating or preventing a disorder associated with the formation and/or the presence of one or more thrombus and to methods of disintegrating one or more thrombus in a patient in need thereof. Furthermore, the invention relates to the use of a pharmaceutically effective amount of ADAMTS13 for the preparation of a pharmaceutical composition for treating or preventing a disorder associated with the formation or the presence of one or more thrombus and for disintegrating one or more thrombus in a patient in need thereof.
L'invention concerne une composition pharmaceutique présentant une activité thrombolytique, contenant la protéase ADAMTS13, et des méthodes permettant le traitement ou la prévention d'un trouble associé à la formation et/ou à la présence d'un ou de plusieurs thrombus, chez un patient nécessitant un tel traitement. L'invention concerne en outre l'utilisation d'une dose pharmaceutiquement efficace de ADAMTS13 pour la préparation d'une composition pharmaceutique destinée à traiter ou à prévenir un trouble associé à la formation ou à la présence d'un ou de plusieurs thrombus, et permettant de désintégrer un ou plusieurs thrombus chez un patient nécessitant ce traitement.
Chauhan Anil Kumar
Plaimauer Barbara
Scheiflinger Friedrich
Wagner Denisa
Baxter Healthcare S.a.
Baxter International Inc.
Cbr Institute For Biomedical Research
Sim & Mcburney
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