Addition copolymers of lactide and glycolide and method of...

Details Addition copolymers of lactide and glycolide and method of... Addition copolymers of lactide and glycolide and method of...

A - Human Necessities

61

L

402/315, 167/323

A61L 17/00 (2006.01) A61L 17/12 (2006.01) C08G 63/08 (2006.01) A61F 2/00 (2006.01)

Patent

CA 1124444

ABSTRACT Relatively high molecular weight, fiber-forming, crystalline copolymers of lactide and glycolide are prepared in a two-stage polymerization process. In the first stage there is prepared a random copolymer of a major proportion of an opti- cally active lactide with a minor proportion of glycolide or d,l-lactide. In the second stage, a major amount of glycolide and a minor amount of lactide monomers are admixed with the co- polymer of the first stage and the polymerization resumed until there is obtained a high molecular weight addition copolymer of lactide and glycolide containing from about 50 to 75 wt percent of units derived from glycolide. The polymer is fiber-forming and useful in the preparation of absorbable surgical sutures.

306056

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