Adeno-associated virus - its diagnostic use with early abortion

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) C07K 14/015 (2006.01) C07K 16/08 (2006.01) C12Q 1/70 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2175256

The present invention relates to a method of detecting a causative agent of the so-called spontaneous early abortion by investigating patients' samples for the presence of adeno-associated virus DNA (AAV DNA), or AAV antigen or antibodies, preferably of the IgM type, directed to AAV. Furthermore, the present invention relates to antibodies suitable for said method.

La présente invention se rapporte à un procédé de détection d'un agent impliqué dans l'avortement dit précoce et spontané, consistant à examiner des échantillons prélevés de patients afin d'y détecter la présence d'ADN de virus adéno-associé (AAV-DNA) ou d'un antigène d'AAV, ou d'anticorps, de préférence du type IgM, dirigés contre l'AAV. La présente invention se rapporte également à des anticorps convenant à un tel procédé.

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