C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 19/16 (2006.01) A61K 31/70 (2006.01)
Patent
CA 2309200
A compound of formula (I) which is an agonist at the adenosine A1 receptor wherein R2 represents C1-3alkyl, halogen or hydrogen; R3 represents a fluorinated straight or branched alkyl group of 1-6 carbon atoms and salts and solvates thereof, in particular, physiologically acceptable solvates and salts thereof. These compounds are agonists at the Adenosine A1 receptor.
L'invention concerne des composé, agoniste du récepteur A1 de l'adénosine, représenté par la formule (I), dans laquelle R?2¿ représente alkyle C¿1-3?, halogène ou hydrogène; R?3¿ représente un groupe alkyle fluoré droit ou ramifié comportant de 1 à 6 atomes de carbone. L'invention concerne également des sels et des solvates, en particulier des sels et des solvates physiologiquement acceptables, dudit composé. Ces composés sont des agonistes du récepteur A1 de l'adénosine.
Cousins Richard Peter Charles
Cox Brian
Eldred Colin David
Pennell Andrew Michael Kenneth
Glaxo Group Limited
Ogilvy Renault
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