Adenosine a3 receptor antagonists

Details Adenosine a3 receptor antagonists Adenosine a3 receptor antagonists

C - Chemistry, Metallurgy

07

D

C07D 417/04 (2006.01) A61K 31/4439 (2006.01) A61P 11/06 (2006.01) A61P 37/08 (2006.01)

Patent

CA 2302417

A pharmaceutical composition for antagonizing adenosine at adenosine A3 receptors which comprises a 1,3-azole compound substituted on the 4- or 5- position, or both, by a pyridyl which may be substituted is provided and can be used as a prophylactic and therapeutic agent for asthma, allergosis, inflammation, and so on.

L'invention concerne une composition pharmaceutique exerçant une action antagoniste à l'encontre de l'adénosine au niveau des récepteurs de l'adénosine A¿3? qui est constituée d'un composé 1,3-azole substitué en position 4- ou 5- ou les deux par un pyridyle qui peut, à son tour, être substitué. La composition peut être utilisée comme agent prophylactique et thérapeutique s'agissant d'asthme, d'allergose, d'inflammation et d'autres maladies analogues.

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