Adenosine derivatives, method for the synthesis thereof, and...

C - Chemistry – Metallurgy – 07 – D

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07D 473/34 (2006.01) A61K 31/4985 (2006.01)

Patent

CA 2680179

Disclosed are adenosine derivatives, methods for the synthesis thereof, and pharmaceutical compositions for the prevention and treatment of inflammatory diseases, comprising the same as an active ingredient. The adenosine derivatives have high binding affinity and selectivity for adenosine receptors, especially for A3 adenosine receptors and act as A3 adenosine receptor antagonists, and exhibit anti-inflammatory activity. Thus, the adenosine derivatives are useful in the prevention and treatment of inflammatory diseases.

L'invention concerne des dérivés d'adénosine, des procédés pour la synthèse de ces derniers, et des compositions pharmaceutiques pour la prévention et le traitement de maladies inflammatoires contenant lesdits dérivés en tant qu'ingrédients actifs. Lesdits dérivés d'adénosine présentent une haute affinité de liaison aux récepteurs d'adénosine ainsi qu'une sélectivité élevée vis-à-vis de ces derniers, en particulier vis-à-vis des récepteurs A3 de l'adénosine; font office d'antagonistes des récepteurs A3 de l'adénosine; et ont une activité anti-inflammatoire. Par conséquent, lesdits dérivés d'adénosine sont utiles dans la prévention et le traitement de maladies inflammatoires.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Adenosine derivatives, method for the synthesis thereof, and... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Adenosine derivatives, method for the synthesis thereof, and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Adenosine derivatives, method for the synthesis thereof, and... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1732207

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.