Adenosine kinase inhibitors comprising lyxofuranosyl...

Details Adenosine kinase inhibitors comprising lyxofuranosyl... Adenosine kinase inhibitors comprising lyxofuranosyl...

C - Chemistry, Metallurgy

07

H

C07H 19/14 (2006.01) C07D 487/04 (2006.01) C07H 19/04 (2006.01) C07H 19/06 (2006.01) C07H 19/16 (2006.01) C07H 19/23 (2006.01)

Patent

CA 2154681

Novel lyxose derivatives which se- lectively inhibit adenosine kinase and methods of preparing these compounds are provided. These compounds are use- ful in treating certain conditions in vivo which may be ameliorated by increased local concentrations of adenosine. The figure depicts levels of acadesine and ZMP in heart tissue after intravenous ad- ministration of compound "A" of the in- stant invention.

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