Adenosine kinase polynucleotides

Details Adenosine kinase polynucleotides Adenosine kinase polynucleotides

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) C07H 21/00 (2006.01) C12N 9/12 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2223181

The present invention provides an isolated and purified polynucleotide that encodes mammalian adenosine kinase, and to an isolated and purified adenosine kinase polypeptide. Human recombinant adenosine kinase and methods of using adenosine kinase polypeptides are also provided. Methods of making recombinant adenosine kinase using those polynucleotides and host cells transformed with those polynucleotides are also provided.

L'invention se rapporte à un polynucléotide isolé et purifié codant pour une adénosine kinase mammifère et à un polypeptide d'adénosine kinase isolé et purifié. L'invention concerne également une adénosine kinase de recombinaison humaine et des procédés d'utilisation de polypeptides d'adénosine kinase. Enfin, l'invention concerne des procédés d'obtention d'adénosine kinase de recombinaison dans lesquels ces polynucléotides sont utilisés ainsi que des cellules-hôtes transformées par lesdits polynucléotides.

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