Adenosine receptor modulators

Details Adenosine receptor modulators Adenosine receptor modulators

A - Human Necessities

61

K

A61K 31/506 (2006.01) A61K 31/465 (2006.01) A61K 31/505 (2006.01) A61P 25/28 (2006.01) C07D 405/04 (2006.01) C07D 405/14 (2006.01)

Patent

CA 2398274

The invention relates to cyclic heteroaromatic compounds, containing at least one nitrogen atom, and to their use in the manufacture of medicaments for the treatment of diseases, related to adenosine receptor modulators, such as Alzheimer's disease, Parkinson's disease, neuroprotection, schizophrenia, anxiety, pain, respiration deficits, depression, asthma, allergic responses, hypoxia, ischaemia, seizure, substance abuse, sedation and they may be active as muscle relaxants, antipsychotics, antiepileptics, anticonvulsants and cardioprotective agents.

L'invention concerne des composés hétéroaromatiques cycliques contenant au moins un atome d'azote, ainsi que leur utilisation dans la fabrication de médicaments destinés au traitement de maladies se rapportant aux modulateurs des récepteurs de l'adénosine, telles que les maladies d'Alzheimer et de Parkinson, ainsi que la neuroprotection, la schizophrénie, l'angoisse, la douleur, les déficits respiratoires, la dépression, l'asthme, les réactions allergiques, l'hypoxie, l'ischémie, l'épilepsie, l'abus de substances psychoactives et des effets sédatifs. Leur activité peut également s'exercer comme relaxants musculaires, antipsychotiques, antiépileptiques, anti-convulsifs et agents cardioprotecteurs.

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