Adenoviral based promoter assay

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01) C12N 15/86 (2006.01) C12N 15/861 (2006.01) C12Q 1/70 (2006.01)

Patent

CA 2334045

Adenoviral vectors are used to transfer a promoter/reporter gene construct to mammalian cell cultures. The promoter/reporter gene construct is used to determine if a candidate inducing agent has promoter-inducing activity; or can be used to determine if a candidate promoter has activity in the presence of a known inducer.

On utilise des vecteurs adénoviraux pour transférer un produit d'assemblage génique promoteur/reporter sur des cultures de cellules de mammifères. Ledit produit d'assemblage sert à déterminer si un agent inducteur candidat présente une activité en présence d'un inducteur connu.

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