Adenoviral mediated gene transfer in adipocytes and related...

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A61K 48/00 (2006.01) A61F 2/02 (2006.01) A61K 31/70 (2006.01) A61K 35/12 (2006.01) C07K 14/52 (2006.01) C12N 5/06 (2006.01) C12N 15/861 (2006.01)

Patent

CA 2259228

The present invention provides gene transfer to adipocytes mediated by adenovirus and, in particular, transfer of toxic genes as a means of reducing adiposity and transfer of genes encoding angiogenic substances to induce new blood vessel growth, as well as adipose tissue implants.

La présente invention porte sur un transfert de gènes vers des cellules adipeuses, ce transfert étant induit par adénovirus, et plus particulièrement, sur le transfert de gènes toxiques servant à réduire l'adiposité ainsi que sur le transfert de gènes codant des substances angiogéniques en vue d'inciter un nouveau développement des vaisseaux sanguins. La présente invention porte également sur des implants de tissu adipeux.

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