Adenoviral-vector-mediated gene transfer into medullary...

A - Human Necessities – 61 – K

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A61K 48/00 (2006.01) A61K 38/18 (2006.01) C12N 15/86 (2006.01) C12N 15/864 (2006.01)

Patent

CA 2277869

The present invention relates to methods and compositions for delivering nucleic acids to motor neurons by administering the nucleic acids to muscle tissue. The invention relates to methods for treating pathologies of the nervous system, such as trauma and neurodegenerative diseases.

L'invention concerne des procédés et des compositions servant à transférer des acides nucléiques dans des motoneurones au moyen de l'administration de ces acides nucléiques au tissu musculaire. Elle concerne des procédés servant à traiter des pathologies du système nerveux, telles que des traumatismes ou des maladies neurodégénératives.

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