Adenoviral vectors encoding erythropoietin and their use in...

Details Adenoviral vectors encoding erythropoietin and their use in... Adenoviral vectors encoding erythropoietin and their use in...

C - Chemistry, Metallurgy

12

N

C12N 15/64 (2006.01) A61K 38/18 (2006.01) A61K 48/00 (2006.01) C07K 14/505 (2006.01) C12N 15/86 (2006.01)

Patent

CA 2339779

Helper dependant adenoviral vectors encoding erythropoietin (epo) provide high levels of epo to achieve a long-term therapeutically effective dosage, and allow for repeat administration to patients with disorders such as anaemia of Chronic Renal Failure (CRF), anaemias due to beta-thalassaemia, and sickle cell anaemia (SCA).

L'invention concerne des vecteurs adénoviraux dépendant des assistants, qui codent pour l'érythropoïétine et fournissent d'importantes quantités d'érythropoïétine permettant d'obtenir des dosages thérapeutiquement efficaces qui peuvent être administrés de manière répétitive aux patients souffrant de troubles tels que l'anémie due à l'insuffisance rénale chronique, les anémies de Cooley et l'anémie des cellules falciformes.

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