C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/86 (2006.01) A61K 35/76 (2006.01) A61K 48/00 (2006.01) C07K 14/785 (2006.01) C12N 5/10 (2006.01) C12N 7/01 (2006.01) C12N 15/861 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2160136
An adenoviral vector including a DNA sequence encoding a lung surfactant protein. The adenoviral vector may be a replication deficient adenoviral vector which is free of at least the majority of the E1 and E3 DNA sequences. Such vectors may be employed for generation of infectious viral particles which may transduce lung epithelial cells in vivo to enable the expression of lung surfactant protein by such cells.
Trapnell Bruce
Whitsett Jeffrey
Genetic Therapy Inc.
Smart & Biggar
University Of Cincinnati
LandOfFree
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