Adenovirus e4 proteins for inducing cell death

Details Adenovirus e4 proteins for inducing cell death Adenovirus e4 proteins for inducing cell death

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61K 31/70 (2006.01) A61K 38/16 (2006.01) C07K 14/075 (2006.01) C12Q 1/42 (2006.01) C12Q 1/70 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2259152

The present invention relates to a pharmaceutical agent for induction of apoptosis for the treatment of human diseases which involve inappropriate cell survival, which includes adenovirus E4orf4, an analog or a biologically active fragment thereof and/or adenovirus E4orf6, an analog or a biologically active fragment thereof. There is also provided a pharmaceutical composition for the treatment of human diseases which involve inappropriate cell survival, which comprises a therapeutic amount of adenovirus E4orf4, an analog or a biologically active fragment thereof and/or adenovirus E4orf6, an analog or a biologically active fragment thereof in association with a pharmaceutical carrier. Included in the invention are methods for identifying compounds as analogs of the adenovirus E4 death proteins.

Agent pharmaceutique destiné à induire l'apoptose pour le traitement de maladies humaines qui donnent lieu à la survie de cellules inappropriées. Ledit agent contient E4orf4 d'adénovirus, ou un analogue ou fragment biologiquement actif de E4orf4 et/ou E4orf6 d'adénovirus, ou un analogue ou un fragment biologiquement actif de E4orf6. La présente invention concerne également une composition pharmaceutique pour le traitement de maladies humaines donnant lieu à la survie de cellules inappropriées, qui comporte une quantité thérapeutique de E4orf4 d'adénovirus, un analogue ou un fragment biologiquement actif de E4orf4 et/ou de E4orf6 d'adénovirus, un analogue ou un fragment biologiquement actif de E4orf6, en association avec un excipient pharmaceutique. La présente invention concerne encore des procédés permettant d'identifier des composés en tant qu'analogues des protéines E4 d'adénovirus entraînant la mort cellulaire.

Affiliated with

Also associated with

Rating

Adenovirus e4 proteins for inducing cell death does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Adenovirus e4 proteins for inducing cell death, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Adenovirus e4 proteins for inducing cell death will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1750815