Adenovirus vectors and method for reducing homologous...

Details Adenovirus vectors and method for reducing homologous... Adenovirus vectors and method for reducing homologous...

C - Chemistry, Metallurgy

12

N

C12N 15/86 (2006.01) C12N 5/10 (2006.01) C12N 15/861 (2006.01)

Patent

CA 2309315

The invention concerns a method for reducing recombination phenomena among nucleic acids. It also concerns the use of said method for producing defective viruses not contaminated by replication particles. The invention further concerns novel viral constructs.

La présente invention concerne une méthode permettant de réduire les événements de recombinaison entre acides nucléiques. Elle concerne également l'application de cette méthode à la production de virus défectifs non contaminés par des particules réplicatives. L'invention concerne également de nouvelles constructions virales.

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