Adenyl-cyclase-hemolysin (ac-hly)-protecting epitopes; use...

Details Adenyl-cyclase-hemolysin (ac-hly)-protecting epitopes; use... Adenyl-cyclase-hemolysin (ac-hly)-protecting epitopes; use...

C - Chemistry, Metallurgy

12

N

C12N 15/60 (2006.01) A61K 39/10 (2006.01) A61K 39/40 (2006.01) C07K 14/235 (2006.01) C07K 16/40 (2006.01) C12N 9/88 (2006.01) C12P 21/08 (2006.01) G01N 33/569 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2180280

L'invention a pour objet des séquences d'acides aminés de l'AC-Hly de B. pertussis, B. parapertussis et/ou B. bronchiseptica, portant des épitopes capables d'induire une réponse immunitaire protectrice contre l'infection par Bordetella. L'invention a pour objet des anticorps, notamment monoclonaux, dirigés contre ces épitopes.

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