Adenylate cyclase in the treatment and/or prophylaxis of...

C - Chemistry – Metallurgy – 07 – K

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C07K 14/235 (2006.01) A61K 39/00 (2006.01) A61K 39/10 (2006.01)

Patent

CA 2542612

Adenylate cyclase toxin (CyaA) or derivative or mutant or fragment or variant or peptide thereof may be used for the treatment and/or prophylaxis of an inflammatory and/or immune-mediated disorder and/or autoimmune disease. The adenylate cyclase toxin (CyaA) is combined with self or foreign antigens or peptides thereof.

Selon l'invention, une toxine d'adénylcyclase (CyaA) ou un dérivé ou mutant ou fragment ou variant ou peptide de ladite toxine peut être utilisé pour le traitement et/ou la prophylaxie d'un trouble inflammatoire et/ou à médiation immunitaire et/ou d'une maladie auto-immune. La toxine d'adénylcyclase (CyaA) de l'invention peut être combinée avec des antigènes propres ou étrangers ou leurs peptides.

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