Adhesion preventive and method of preventing adhesion

A - Human Necessities – 61 – L

Patent

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Details

A61L 31/00 (2006.01) A61K 31/785 (2006.01) A61P 7/04 (2006.01) A61P 41/00 (2006.01)

Patent

CA 2585502

It is intended to provide an adhesion preventive by which the adhesion of the surface of an organ can be effectively prevented and which is absorbed in the body, has a high safety, can be easily produced and, therefore, is highly useful in practice; and a method of preventing adhesion by using this adhesion preventive. Namely, (1) an adhesion preventive containing a water-absorbing crosslinked .gamma.-polyglutamic acid compound as the active ingredient; (2) the adhesion preventive as described above wherein the water-absorbing crosslinked .gamma.-polyglutamic acid compound is in the form of a powder having a water absorption rate of from 800 to 2000; (3) a method of preventing the adhesion of an organ characterized by bringing the adhesion preventive as described above into contact with the topical organ surface; and (4) the method of preventing adhesion as described above wherein the topical organ surface is in the moist state.

L~invention concerne un préventif d~adhésion grâce auquel l~adhésion de la surface d~un organe peut être empêchée de manière efficace, qui est absorbé dans le corps, présente un haut degré de sécurité, peut être produit facilement et est donc utile dans la pratique ; ainsi qu~un procédé destiné à prévenir l~adhésion en utilisant ce préventif d~adhésion. L~invention concerne notamment (1) un préventif d~adhésion contenant un composé hygroscopique réticulé à base d~acide .gamma.-polyglutamique en tant que principe actif ; (2) le préventif d~adhésion tel que décrit ci-dessus, dans lequel le composé hygroscopique réticulé à base d~acide .gamma.-polyglutamique est présent sous la forme d~une poudre ayant un taux d~absorption d~eau de 800 à 2000 ; (3) un procédé destiné à empêcher l~adhésion d~un organe, caractérisé par la mise en contact du préventif d~adhésion tel que décrit ci-dessus avec la surface topique de l~organe ; et (4) le procédé destiné à empêcher l~adhésion tel que décrit ci-dessus, dans lequel la surface topique de l~organe est dans un état humide.

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