Adhesion protein micelles

Details Adhesion protein micelles Adhesion protein micelles

C - Chemistry, Metallurgy

07

K

167/129, 530/13,

C07K 9/00 (2006.01) A61K 9/107 (2006.01) A61K 9/127 (2006.01) A61K 9/133 (2006.01) A61K 38/17 (2006.01) A61K 39/00 (2006.01) A61K 47/48 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1338079

A micelle of an adhesion protein which naturally includes a phosphatidylinositol lipid anchor, the micelle being capable of binding multivalently to a plurality of target molecules on a cell surface. The micelle can be used to ameliorate diseases in which binding of T-cells to other cells is a continuing factor, e.g. in autoimmune diseases like rheumatoid arthritis, allograft rejection and graft-versus-host diseases.

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