Adhesion receptor antagonists

Details Adhesion receptor antagonists Adhesion receptor antagonists

C - Chemistry, Metallurgy

07

K

C07K 5/02 (2006.01) A61K 31/42 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) A61K 31/55 (2006.01) A61K 38/05 (2006.01) A61K 38/06 (2006.01) C07D 263/20 (2006.01) C07D 263/24 (2006.01) C07D 413/06 (2006.01) C07D 413/10 (2006.01) C07D 413/14 (2006.01) C07K 5/06 (2006.01)

Patent

CA 2156360

Compounds of the formula I (see formula I) , in which R1 and X have the given meanings, their physiologically unobjectionable salts and/or solvates inhibit the binding of fibrinogen to the corresponding receptor and can be employed for the treatment of thromboses, osteoporosis, tumoural diseases, apoplexy, cardiac infarction, inflammations, arteriosclerosis and osteolytic disorders.

L'invention concerne des composés de la formule I (voir formule I), dans laquelle R1 et X ont la signification donnée, leurs sels admissibles sur le plan physiologique et/ou les solvates inhibent la fixation de fibrinogène au récepteur correspondant et peut être employé pour le traitement de thromboses, de l'ostéoporose, des maladies cancéreuses, de l'apoplexie, des infarctus cardiaques, des inflammations, de l'artériosclérose et des troubles d'ostéolyses.

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