Adhesive compositions for the hard tissues of the human body

Details Adhesive compositions for the hard tissues of the human body Adhesive compositions for the hard tissues of the human body

C - Chemistry, Metallurgy

07

F

C07F 9/113 (2006.01) A61C 5/00 (2006.01) A61K 6/00 (2006.01) C07F 9/09 (2006.01)

Patent

CA 2340900

An adhesive composition is provided which is suitable for the bonding of polymeric materials, in whole or in part, such as composite resins, or methacrylate-containing glass-ionomer filling materials, to tooth enamel, or tooth dentin, or to other hard tissues of the human body, such as bone. The composition comprises an unsaturated carboxylic acid ester, an unsaturated phosphate ester and other crosslinking agents. The especially preferred phosphates (which are provided as new compounds) are those of formula (I) in which: R1 is a hydrogen atom, alkyl C1-C4, or CN; R is an aliphatic, cycloaliphatic or aryl radical containing from 1 to 10 carbon atoms and having a valence of n+1; n is an integer from 1 to 5, preferably from 3 to 5.

La présente invention concerne une composition adhésive convenant au collage total ou partiel de matières polymères, telles que les résines composites, les matières de remplissage de verre ionomère renfermant du méthacrylate, sur l'émail des dents, sur la dentine, ou sur d'autres tissus durs du corps humain, comme les os. Cette composition comprend un ester d'acide carboxylique non saturé, un ester phosphorique non saturé, et d'autres agents de réticulation. Les phosphates particulièrement préférés (qui sont présentés comme nouveaux composés) sont représentés par la formule (I), dans laquelle R¿1? représente un atome d'hydrogène, un alkyle C¿1?-C¿4? ou un CN, R représente un radical aliphatique, cycloaliphatique ou aryle comprenant entre 1 et 10 atomes de carbone et présentant une valence de n+1, n représentant un nombre entier compris entre 1 et 5, de préférence entre 3 et 5.

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