Adhesive for percutaneously absorbable patch and...

A - Human Necessities – 61 – K

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Details

A61K 47/30 (2006.01) A61K 9/70 (2006.01) A61K 47/18 (2006.01) A61K 47/22 (2006.01)

Patent

CA 2284625

Pressure-sensitive adhesives for percutaneous plasters capable of containing crotamiton at a high concentration. These adhesives contain pyrothiodecane as a compatibilizer for crotamiton. In particular, they comprise 10 to 40 % by weight of (A-B)n-A type elastic block copolymers, 10 to 45 % by weight of liquid paraffin, 3 to 10 % by weight of crotamiton and 0.3 to 10 % by weight of pyrothiodecane as a compatibilizer for crotamiton. The percutaneous plasters contain these adhesives and drugs.

La présente invention concerne des adhésifs autocollants pour emplâtres percutanés pouvant contenir une crotamitone à concentration élevée. Ces adhésifs contiennent un pyrothiodécane comme un agent de compatibilisation pour la crotamitone. Ils comprennent, en particulier, 10 à 40 % en poids de copolymères blocs élastiques de type (A-B)¿n?-A, 10 à 45 % en poids de paraffine liquide, 3 à 10 % en poids de crotamitone et 0,3 à 10 % en poids de pyrothiodécane comme agent de compatibilisation pour la crotamitone. Les emplâtres percutanés contiennent lesdits adhésifs et des médicaments.

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