Adhesive hydrogels having extended use lives and process for...

C - Chemistry – Metallurgy – 09 – J

Patent

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C09J 11/06 (2006.01) A61K 9/70 (2006.01) A61K 47/10 (2006.01) A61K 47/30 (2006.01) A61K 47/32 (2006.01) A61L 15/44 (2006.01) A61L 15/58 (2006.01) A61L 15/60 (2006.01) A61L 24/00 (2006.01) A61L 26/00 (2006.01) C08K 5/00 (2006.01) C08L 39/06 (2006.01) C08L 71/02 (2006.01) C09J 139/06 (2006.01) C09J 171/02 (2006.01)

Patent

CA 2123487

2123487 9310163 PCTABS00022 This invention relates to a non-stringy adhesive hydrophilic gel comprising an aqueous mixture of a radiation crosslinkable water-soluble polymer, at least one humectant effective to extend the moisture retaining characteristics of the gel and which inhibits the ability of radiant energy to crosslink the water-soluble polymer, a pharmacologically active agent, and a crosslinking promoter effective to counteract the crosslinking inhibitory effect of humectant. The aqueous mixture is exposed to radiant energy effective to provide a non-stringy adhesive cohesive homogeneous hydrophilic gel that has an extended in-use lifetime. The gels can be formed into PATCHES for long term application of the pharmacologically active agent to a patient.

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