Adhesive preparation comprising sufentanil and methods of...

Details Adhesive preparation comprising sufentanil and methods of... Adhesive preparation comprising sufentanil and methods of...

A - Human Necessities

61

K

A61K 9/70 (2006.01) A61K 31/4468 (2006.01) A61P 25/04 (2006.01)

Patent

CA 2642338

The present invention provides percutaneously absorbable adhesive preparations and transdermal compositions comprising Sufentanil, which are obtained from economic starting materials, have a constitution simpler than that of conventional Sufentanil adhesive preparation and have effective skin permeability. The preparations and compositions comprise two polyisobutylenes having different molecular weights, a tackifier, a permeation enhancer.

La présente invention concerne des préparations adhésives pouvant être absorbées par voie percutanée et des compositions transdermiques comprenant du Sufentanil, qui sont obtenues à partir de matériaux de départ économiques, ont une composition plus simple que celle d'une préparation adhésive au Sufentanil traditionnelle et ont une perméabilité dermique efficace. Les préparations et compositions comprennent deux polyisobutylènes ayant des masses moléculaires différentes, un agent poisseux, un adjuvant de perméation.

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