Adhesive skin patch and method for evaluation of adhesive...

A - Human Necessities – 61 – K

Patent

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A61K 47/32 (2006.01) A61K 9/70 (2006.01)

Patent

CA 2670971

Disclosed is an adhesive skin patch having an SIS block copolymer as an adhesive component, which has an improved handling property and can reduce irritation to a user. The adhesive skin patch comprises a flexible substrate and an adhesive layer laminated on the substrate, wherein the adhesive layer comprises a styrene-isoprene-styrene block copolymer. In the adhesive skin patch, the tan.delta. value of the adhesive agent as determined by measuring a dynamic viscoelasticity at 32ºC satisfies a requirement represented by the following formula 1 at at least one frequency laying between 0.04 to 0.25 Hz. 0.25x + 0.05 <= y <= 0.25x + 0.10 (formula 1) [wherein x represents a frequency (Hz); and y represents a tan.delta. value.]

L'invention concerne un patch cutané adhésif présentant un copolymère en bloc SIS en tant que composant adhésif, doté d'une propriété de maniement améliorée et capable de réduire l'irritation chez un utilisateur. Ledit patch cutané adhésif comprend un substrat flexible et une couche adhésive laminée sur ledit substrat, ladite couche adhésive comprenant un copolymère en bloc styrène-isoprène-styrène. Dans ledit patch cutané adhésif, la valeur tan.delta. de l'agent adhésif telle que déterminée par la mesure d'une viscoélasticité dynamique à 32ºC satisfait une exigence représentéepar la formule suivante à au moins une fréquence située entre 0,04 et 0.,25 Hz. 0,25x + 0,05 <= y <= 0,25x + 0,10 (formule 1) [x représentant une fréquence (Hz) ; et y représentant une valeur tan.delta..]

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