Adipogenic adenoviruses as a biomarker for disease

A - Human Necessities – 61 – K

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A61K 39/23 (2006.01) C12Q 1/70 (2006.01)

Patent

CA 2635269

This invention relates to the relationship between infection with adipogenic adenoviruses, such as adenovirus-36 (Ad-36) and the etiologies of obesity and obesity-related cancers and other diseases. Additionally, the invention relates to assaying a subject for Ad-36 status and using Ad-36 status as a marker for the presence of cancer, to predict the future risk of developing cancers, such as breast or prostate cancer, and/or to predict the aggressiveness and prognosis of these cancers.

Cette invention concerne la relation entre une infection par des adénovirus adipogènes tels que l'adénovirus-36 (Ad-36) et les étiologies de l'obésité et des cancers liés à l'obésité et autres maladies. De plus, l'invention porte sur le dosage d'un sujet pour l'état Ad-36 et l'utilisation de l'état Ad-36 en tant que marqueur pour la présence de cancer, pour prédire le risque futur de développer des cancers, tels que le cancer du sein ou de la prostate, et/ou pour prédire l'agressivité et le pronostic de ces cancers.

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